| Ryan Powell replaces namesake Matt Powell and Brown comes in for Loki Crichton as Warriors hunt a first away win in the league this campaign.
Director of Rugby Mike Ruddock also hands a recall to Drew Hickey who takes the place of Tom Wood in the back row.
However, prop Darren Morris is ruled out with a stinger injury and his place in the front row goes to Tony Windo who will make his first league start since October.
Youngster Callum Black misses the game with a shoulder injury and his spot on the bench goes to Shaun Ruwers, who signed a new two-year deal this week. Wing Marcel Garvey is also named among the replacements.
Warriors v Harlequins
15 Thinus Delport
14 Rico Gear
13 Dale Rasmussen
12 Sam Tuitupou
11 Miles Benjamin
10 James Brown
9 Ryan Powell
1 Tony Windo
2 Aleki Lutui
3 Tevita Taumoepeau
4 Greg Rawlinson
5 Craig Gillies
6 Drew Hickey
7 Pat Sanderson (c)
8 Kai Horstmann
16 Shaun Ruwers
17 Matt Mullan
18 Will Bowley
19 Netani Talei
20 Matt Powell
21 Loki Crichton
22 Marcel Garvey
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